A Cure is Here

Given my intense irritation recently at the Anti-Safety, Pro-COVID-19 propagators in the news and their public defiance of intelligent, virological Social-distancing and Stay-at-Home Orders—while coronavirus infections continue to rise in alarming numbers—I thought it would be fantastic to post some remarkable, positive humanitarian news in the area of science and medical therapies in the fight against cancer! After all, we reasonable, well-educated people have been in need for an exciting story that reinforces the enriching necessity for expert, scholarly science, breakthrough medical science especially that ushers hundreds and hundreds of happy results, happy recoveries, and lengthy remissions! Ah, every so often something good does come out of Texas! It’s good to be proven wrong sometimes.

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Dr. Allison, the 2018 Nobel Prize Co-Winner in Physiology or Medicine, is the subject of a riveting documentary that shows the spotlight on his groundbreaking work and serves as a stark, prophetic reminder of the obligation for extensive science in the year of COVID-19. Perhaps COVID-20 as well.

Last night I was fortunate to catch the broadcast by PBS’ Independent Lens the documentary film Jim Allison: Breakthrough. Boy was it a much needed encouragement and frequent cheer-leading shouts of “YES, OH MY STARS & GALAXIES,” and “I LOVE YOU SCIENCE” that I needed right now. Watching too much current news can really begin to dampen and darken your spirit for life. Your levels of endorphins, dopamine, and oxytocin can suffer from too much prolonged cortisol.

From our own University of Texas MD Anderson Cancer Center website on Dr. Allison’s astounding research and work. I highly recommend reading the entire webpage:

Immunotherapy innovator Jim Allison’s Nobel purpose, some excerpts

Jim Allison, Ph.D., chair of Immunology and executive director of the immunotherapy platform, pioneered a revolutionary cancer treatment that frees the immune system to attack tumors.

“By stimulating the ability of our immune system to attack tumor cells, this year’s Nobel Prize laureates have established an entirely new principle for cancer therapy”

[…]

Allison showed that the protein CTLA-4, which is found on the surface of T cells, acts as a brake — a type of immune system checkpoint the body uses to avoid a dangerously over-reactive immune response. He then developed an antibody to block CTLA-4’s “braking” action, freeing T cells to attack cancer.

His work and determination led to the development of Ipilimumab, the first in a class of drugs known as checkpoint inhibitors. In 2011, the drug — commercially named Yervoy — was approved for late-stage melanoma by the Food and Drug Administration. It has yielded unprecedented results. Twenty percent of patients with advanced melanoma who took the drug now live for at least three years, and many live 10 years and beyond.

[…]

Crucial funding for his research over the years has come from the National Institutes of Health, particularly the National Cancer Institute, the Cancer Prevention & Research Institute of Texas, Howard Hughes Medical Institute, the Cancer Research Institute, Prostate Cancer Foundation, Stand Up To Cancer and PICI.

Toward the end of this documentary film Dr. Allison is reading a letter he received from a lady, a wife, a total stranger. I am not going to spoil it for you, but it is definitely a moment that all we human beings with a grateful, compassionate, unselfish heart must hear/read more often than not. Perspective needed. This is unprecedented news in this daunting, beautiful life we’ve been privileged to live, inside this tiny minuscule space in time, on one tiny, tiny pale-blue rock among billions and billions of other stars and planets in our ONE little galaxy… among billions or trillions of other galaxies. It is called the Overview Effect. Get some.

Share any thoughts below you might have once you’ve watched the film, or not watched if you’re already familiar with this man’s phenomenal work and dedication over many decades of incessant persistence. It is truly a man, a scientist, and story to greatly admire. I do.

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Live Well — Love Much — Laugh Often — Learn Always — Stay Curious!

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8 thoughts on “A Cure is Here

    • I sure needed it John. For the last 6-8 weeks or more all epidemiologists, virologists, experienced medical staff who fought against SARS and MERS, all of the true medical experts repeat the same warning to the public over and over and over…

      Normal life, “business as usual” CANNOT BEGIN UNTIL THE INFECTIOUS CASE NUMBERS CONTINUOUSLY GO DOWN OVER AT LEAST A 2-WEEK PERIOD!!! If we try to return to normal while infection numbers are still rising—HELL, going thru the roof!!!—then it is guaranteed we will make the exact same mistake too many cities and states made in 1918-19 by reopening prematurely, worst of all while infections are still alarmingly rising!!!! If that happens, we WILL OVERRUN our hospitals, their beds, and worst of all… the very medical staff we NON-scientists need to survive!!! F*CKING HELL, can I say it anymore clearly!??? 🤬😠

      John, I don’t understand why ordinary people, who DO NOT SPECIALIZE in infectious diseases, let alone don’t spend a lifetime career studying in the field and all the breaking news, discoveries, etc, about the Earth’s 9-10 other fatal, deadly, highly contagious viruses we DO KNOW something about… and then publicly proclaim themselves “knowledgeable experts” to speak authoritatively! Are they TRYING to mimic our President!? What fools we have in this country and how easily our media services ignorantly give them mega-phones and microphones.

      Man do we need many more Jim Allisons here, don’t we?

      Liked by 1 person

  1. “a riveting documentary”??? Guess it’s all in the eye of the beholder. 😉

    Seriously, while it isn’t something I would watch, the topic it covers IS good news. Which is greatly needed right now. *sigh*

    Liked by 2 people

    • Hahaha! You are right Nan. 😉 It is all subjective behavior. I will certainly admit that during these very frustrating, irritating weeks listening to, watching, and reading about these defiant Pro-COVID-19 propagators protesting, this documentary was a HUGE welcomed relief and did get me riveted or excited. 😛

      Like

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