A Cure is Here

Given my intense irritation recently at the Anti-Safety, Pro-COVID-19 propagators in the news and their public defiance of intelligent, virological Social-distancing and Stay-at-Home Orders—while coronavirus infections continue to rise in alarming numbers—I thought it would be fantastic to post some remarkable, positive humanitarian news in the area of science and medical therapies in the fight against cancer! After all, we reasonable, well-educated people have been in need for an exciting story that reinforces the enriching necessity for expert, scholarly science, breakthrough medical science especially that ushers hundreds and hundreds of happy results, happy recoveries, and lengthy remissions! Ah, every so often something good does come out of Texas! It’s good to be proven wrong sometimes.

∼ ∼ ∼ § ∼ ∼ ∼

Dr. Allison, the 2018 Nobel Prize Co-Winner in Physiology or Medicine, is the subject of a riveting documentary that shows the spotlight on his groundbreaking work and serves as a stark, prophetic reminder of the obligation for extensive science in the year of COVID-19. Perhaps COVID-20 as well.

Last night I was fortunate to catch the broadcast by PBS’ Independent Lens the documentary film Jim Allison: Breakthrough. Boy was it a much needed encouragement and frequent cheer-leading shouts of “YES, OH MY STARS & GALAXIES,” and “I LOVE YOU SCIENCE” that I needed right now. Watching too much current news can really begin to dampen and darken your spirit for life. Your levels of endorphins, dopamine, and oxytocin can suffer from too much prolonged cortisol.

From our own University of Texas MD Anderson Cancer Center website on Dr. Allison’s astounding research and work. I highly recommend reading the entire webpage:

Immunotherapy innovator Jim Allison’s Nobel purpose, some excerpts

Jim Allison, Ph.D., chair of Immunology and executive director of the immunotherapy platform, pioneered a revolutionary cancer treatment that frees the immune system to attack tumors.

“By stimulating the ability of our immune system to attack tumor cells, this year’s Nobel Prize laureates have established an entirely new principle for cancer therapy”

[…]

Allison showed that the protein CTLA-4, which is found on the surface of T cells, acts as a brake — a type of immune system checkpoint the body uses to avoid a dangerously over-reactive immune response. He then developed an antibody to block CTLA-4’s “braking” action, freeing T cells to attack cancer.

His work and determination led to the development of Ipilimumab, the first in a class of drugs known as checkpoint inhibitors. In 2011, the drug — commercially named Yervoy — was approved for late-stage melanoma by the Food and Drug Administration. It has yielded unprecedented results. Twenty percent of patients with advanced melanoma who took the drug now live for at least three years, and many live 10 years and beyond.

[…]

Crucial funding for his research over the years has come from the National Institutes of Health, particularly the National Cancer Institute, the Cancer Prevention & Research Institute of Texas, Howard Hughes Medical Institute, the Cancer Research Institute, Prostate Cancer Foundation, Stand Up To Cancer and PICI.

Toward the end of this documentary film Dr. Allison is reading a letter he received from a lady, a wife, a total stranger. I am not going to spoil it for you, but it is definitely a moment that all we human beings with a grateful, compassionate, unselfish heart must hear/read more often than not. Perspective needed. This is unprecedented news in this daunting, beautiful life we’ve been privileged to live, inside this tiny minuscule space in time, on one tiny, tiny pale-blue rock among billions and billions of other stars and planets in our ONE little galaxy… among billions or trillions of other galaxies. It is called the Overview Effect. Get some.

Share any thoughts below you might have once you’ve watched the film, or not watched if you’re already familiar with this man’s phenomenal work and dedication over many decades of incessant persistence. It is truly a man, a scientist, and story to greatly admire. I do.

————

Live Well — Love Much — Laugh Often — Learn Always — Stay Curious!

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Permissions beyond the scope of this license may be available at https://professortaboo.com/contact-me/.

Cash-worshipers vs. COVID-19

The madness, the sheer ignorance, or insanity of this modern life, of complacency and certain human logic often cannot be fathomed, not in the least. Today I am beside myself.

A wealthy women’s Republican organization took to the grounds of Dealey Plaza in downtown Dallas Tuesday, April 21st, 2020 demanding businesses reopen and workers return to their jobs immediately. Their demands came in the wake of still rising confirmed infections of COVID-19 cases of 2,602 (90 more cases) on April 20th from 2,190 on April 15th, including 9 additional deaths in those five days. Confirmed COVID-19 cases in Dallas County are still rising according to the Dallas County Health and Human Services.

PCRW protest Dallas

The Park Cities Republican Women is a political club of wives and women from two of Texas’ most wealthiest urban municipalities within Texas, University Park and Highland Park combined, and second only to Collin County consisting of opulent towns like Plano, McKinney, and Allen, Texas. These two counties are the bulk of the wealthiest Republican seats in North Texas for the last 25-30 years. Some of the nation’s richest billionaires live in three of these four Dallas neighborhoods. At one time in recent history these neighborhoods all barred non-whites from entering these areas of residence.

Park Cities Republican Women Board

Dallas Park Cities Republican Women Executive Board

Researching and digging into these ladies’ current occupations and their husbands’ and those business ties and ventures certainly yielded a very clear bias leaning to DFW mega-businesses in sectors like but not limited to real estate, financial-wealth management, and mass media corporations. That digging also resulted in determining that several of these women on the “Executive Board” are not native Texans or even more than 3rd-4th generation Texans. It soon begs the question, How many times have these ladies gone to and spent significant time in Dallas’ most impoverished areas (Pleasant Grove? Wynnewood or Beckley Club Estates?) for simple charity or stimulus packages/plans for critically needed improvement in basic, public socio-educational programs?

Aside from these protester’s political associations and postures the more pressing, more critical question to be asked is what is required to stop and reduce COVID-19 infections and subsequent deaths. After all, is it not human life, the unnecessary loss of innocent lives that are most important, most morally responsible that is the top priority? Isn’t that the highest importance as if it were your own child or your own parent? Is that an overreaction by anyone who’s own child/parent might be infected with COVID-19?

Overreaction? Seriously!? What planet do you live on!?

No. It is anything but an overreaction people. As of today, April 25, 2020, there are 2.79-million people infected by COVID-19 around the world. To date there have been 196,000 deaths from coronavirus; over 52,400 in the U.S. and rising still. All one need do is examine Italy’s COVID-19 crisis in March 2020.

italy_newplot

From a March 23rd Vox article:

What’s scary about Italy’s experience is that Italy wasn’t exactly passive in its response to the virus. The country did act, quarantining a dozen towns in northern regions on February 23, urging the public to engage in social distancing, and ordering the closure of all schools nationwide on March 4.

The reality, however, of wisely and scientifically managing one of the worst, most devastating pandemics this country has faced since January 1918 with the Spanish Flu pandemic, is that there is a very specific, safe plan to slowly ease out of Social-distancing and Stay-at-Home orders that were ordered to save lives. It is simply called public health and protection of American lives directed and implemented by our elected government officials, on all necessary levels. That’s the theory anyway.

The plan has several phases: Phase one is slowing the spread through social distancing, while ramping up testing capacity, and ensuring hospitals have the equipment they need. In phase two, social distancing restrictions ease while public health workers continue to track and isolate cases.

But it will take a lot to get there. The authors argue these decisions need to be made on a region-by-region basis: Phase two should only begin after 14 days of sustained case reductions in an area, and only after testing capacity is dramatically increased.
Resnick, Brian, “How to safely end social distancing,” Vox.com, accessed April 25, 2020

There is still so much that is unknown, undetermined about the COVID-19 virus, how it spreads so easily, so quickly, and how it is quickly detected. We just learned that six more symptoms have been added to the original 4-5 symptoms. On top of this new evidence there are people in China and Japan that after recovering from infection they have become reinfected with COVID-19. The fact is there is simply not enough collected data and research to determine with certainty whether these new cases were in fact positively infected the first time (U.N. announcement). Therefore, with a known incubation period of at least 14-days before COVID-19 symptoms manifest in patients, it is much more safe for medical professionals and the general public to err on the side of caution.

Remarkably there is still push-back from many Cash-worshipers. The Park Cities Republican Women’s club is not the only protesters voicing their defiance. Lulu Garcia-Navarro hosts NPR’s Weekend Edition Sunday and she along with Kirk Siegler talked with former Salt Lake City, Utah police officer Eric Moutsos who has become overly vocal since being put on administrative leave from the SLC police department:

In my opinion, not being able to provide for your family is a hundred times bigger health crisis than any virus.

Quarantine is for sick people. It’s when you lock sick people away. But when you lock healthy people away, that’s tyranny.

Moutsos is not alone in his self-made celebrity status. Texas Lt. Governor Dan Patrick has already made controversial remarks against the sanctity of life for all Americans by stating senior citizens were more concerned about money, paychecks, and the economy. From NBCnews.com:

“And what I said when I was with you that night, there are more important things than living. And that’s saving this country for my children and my grandchildren and saving this country for all of us,” Patrick said Monday night.

He went on to say that he didn’t want to die but that “we’ve got to take some risks and get back in the game and get this country back up and running.”

On the contrary, reality according to epidemiologists and virologists around the world is that too many Americans are underestimating how long COVID-19 disruptions will have to last. They blame much of this false hope on the Trump Administration’s erroneous information and timelines disseminated in Press Conferences:

…but quickly reopening businesses or loosening shelter-in-place rules would inevitably lead to a new surge of infections, they said.

“The administration has consistently shown a desire to underplay the severity of whatever is coming. And they’re constantly adjusting that — as it becomes harder to deny the reality will be worse than what they’ve conditioned people for,” said Jeremy Konyndyk, a senior policy fellow at the Center for Global Development.

But experts say that, even if some restrictions are relaxed, it’s unlikely life as normal will resume in early May.

“Decisions to reopen society should not be about a date, but about the data,” Frieden, now president and CEO of the global public health initiative Resolve to Save Lives, said during a briefing Wednesday for journalists. “How well and how quickly we do these things will determine how soon and how safely we can reopen.”

Still A Small Minority

Fortunately, these protesting Cash-worshipers represent a small minority in the U.S. as well as Texas. The Texas Tribune’s Brandon Formby and Ross Ramsey write:

Two-thirds of registered Texas voters agree with decisions by Gov. Greg Abbott and several local officials to suspend nonessential business operations. And more than three-quarters of voters support orders to stay home except for essential activities. The poll’s findings come as Abbott says he will soon announce plans to reopen a wide range of Texas businesses.

According to Politico.com only 30% of Americans say getting the nation’s economy up and running is a first priority despite what some news media corporations promote. Here is what Gallup Polling states:

The average American is unequipped to make scientific judgments on virus-related matters. Americans are better able to make judgments on the financial and economic impact of the shutdowns.

While other Gallup data show that a majority of Americans (55%) say they can continue following social distancing practices without significant financial hardship for “as long as is necessary,” 8% say they’re already experiencing significant financial hardship, and another 14% say they will within a few more weeks.

[…]

58% of respondents in the survey chose… “the United States will move too quickly in loosening restrictions and the virus will continue to spread with more lives being lost.”

As of today, the majority of Americans do not want to risk more extended restrictions of Stay-at-Home orders by foolishly and prematurely reopening. This is clear.

Will American History Repeat Itself?

Assistant Director of the Center for the History of Medicine at Michigan University, Alex Navarro, detailed the historical accounts of the 1918 Spanish flu in 43 cities:

“There was a lot of pressure in pretty much all of these American cities to reopen,” said Navarro, whose research was done in conjunction with the Centers for Disease Control and Prevention. “When they removed those restrictions too soon, then many cities saw a resurgence in cases.”

Government authorities in California and much of the West Coast in 1918 – 1919 were doing everything right, they were ‘flattening the curve’ as repeatedly told by doctors and scientists of virology and epidemiology. Sadly, by November and December 1918 too many business leaders and moguls put huge pressure on government officials to reopen and return our struggling economy to normal. Those Cash-worshipers then used the press to further promote and propagandize their declining riches.

San-Francisco-influenza-1918

A congregation praying on the steps of the Cathedral of Saint Mary of the Assumption, where they gathered to hear mass and pray during the influenza epidemic, San Francisco, California, 1918 — Hulton Archive / Getty Images

But three weeks after that celebration of removing their masks, the city saw a dramatic resurgence. Officials at first rejected the idea of reopening the city and suggested residents could voluntarily wear face coverings.

But shortly after the New Year in 1919, the city was hit with 600 new cases in one day, prompting the Board of Supervisors to re-enact the mandatory mask ordinance. Protests against the mandate eventually led to the formation of the Anti-Mask League. The detractors eventually got their way when the order was lifted in February.

And as PBS’ poignant Frontline documentary Coronavirus Pandemic proved this past Tuesday, April 21st, the American economy is not just taking a blow from COVID-19, the nation’s economy is suffering directly because of Washington D.C., the White House, and specifically our incapable fake President who delayed and downplayed the seriousness of the virus. He has never been a true leader prior to or during his Presidency or one who proactively or consistently shows compassion, sympathy and empathy for all Americans, or much less the ability to admit publicly when you’ve truly f*cked up. Has the man ever taken full responsibility for his f*ck ups as the country’s incapable leader? The truth doesn’t get any simpler nor more clear.

Nevertheless, getting back to the real issue: the science, when your country’s top, foremost doctor of infectious diseases Dr. Anthony Fauci states If it looks like you’re overreacting, you’re probably doing the right thing then even a preschooler understands what must be done no matter how badly your pocketbook is hurting. Duh!

∼ ∼ ∼ § ∼ ∼ ∼

Addendum 4/28/2020 — this is an excellent interview by Michel Martin of PBS’ Amanpour & Company called “Former Sen. Bill Frist on the President’s Pandemic Response.” It is well worth watching:
https://www.pbs.org/video/former-sen-bill-frist-presidents-pandemic-response-h6futh/

————

Live Well — Love Much — Laugh Often — Learn Always — Listen to Experts

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Permissions beyond the scope of this license may be available at https://professortaboo.com/contact-me/.

Tiptop Improv Returns!

When I had heard that one of my all-time favorite comedy shows was returning for at least one more, maybe two more seasons, my jaw dropped and I let go the screaming SHUT THA FRONT DOOR!!!! shoving my friend over the side of the couch. From years gone by… back to my prim-ier years (Drew Carey hosted), even to my days right out of college (Clive Anderson hosted) when my Dad and I watching religiously, laughing non-stop! Was it really happening? Could it be? It was indeed a dream come true, reborn.

Whose Line Is It Anyway was back on the air with the usual suspects Colin Mochrie, Ryan Stiles, Wayne Brady, a special guest, and hosted by Aisha Tyler. I frackin’ frickin’ fruitin’ LOVE this show! Let the predictable unpredictable rib-breaking commence!

————

Pure unadulterated laughter, the best medicine. If you used to watch this entertaining hyper-ventilating 30-mins of hilarity and have any favorite scenes, share them below if you can! All are welcomed!

————

Live Well — Love Much — Laugh Often — Learn Always

Creative Commons License
Blog content with this logo by Professor Taboo is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Permissions beyond the scope of this license may be available at https://professortaboo.com/contact-me/.